Thursday, 24 March 2011

#Menopause Matters event

Menopause Matters is a free afternoon event for women in Carlisle – with leading specialist in the field Dr Heather Currie leading the session.

Dr Currie is the founder of and she will be joined on the day by local specialist Dr Jenny Lyons of Carlisle.

Supported by Carlisle Partnership, the event will take place at Tullie House in Carlisle on Tuesday, March 29 from 12 noon until 4.30pm.

There will be information and advice on everything from diet and fitness to skin and beauty.

For more information or to book a free place at the event  visit  or call 01228 409090.

Tuesday, 8 March 2011

#Menopausal #hormone therapy and cardiovascular disease

Cardiovascular disease remains the single largest cause of death in women. Much interest has been shown in the effects of Hormone Replacement Therapy on the risk of cardiovascular disease, with observational studies showing a significant reduction in risk, and randomised controlled trials (RCTs) showing an increase.
The Timing Hypothesis suggests that the time since menopause that HRT is commenced influences the effect of hormones on the cardiovascular system and continues to be questioned as an explanation for the discrepant outcomes. A group has recently reported on the evidence regarding the basis of the hypothesis and its suitability to explain differences in outcomes between trials of hormone therapy commenced early following the menopause, as in observational studies, and therapy which is delayed as in RCTs.
From a literature review, reports of laboratory, animal and human studies were shown to support the different effect of HRT on normal versus diseased vessels, with a beneficial effect when HRT is commenced early with healthy blood vessels, compared to a negative effect when therapy is delayed with vascular disease. Age and time since menopause have been related to the extent of vascular disease in women. The group concluded that there is ample evidence of the validity of the Timing Hypothesis as an explanation of the different outcomes of observational studies and RCTs and recommend that research on cardiovascular disease prevention by early HRT should be the highest national priority.
Read more about Menopause, hormones and cardiovascualr disease at